arXiv cs.LG
· Papers
Two Stages of Folding: Convergent Mechanisms in AI Protein Folding Trunks
arXiv:2602.06020v3 Announce Type: replace Abstract: How do protein structure prediction models fold proteins? We investigate this question through causal interventions on the folding trunks of ESMFold, OpenFold, and Boltz-1. Across all three models, we find a shared two-stage computational structure. In the first stage